Degree of serotonin reuptake inhibition of antidepressants and ischemic risk
نویسندگان
چکیده
منابع مشابه
Inhibition of Serotonin Reuptake
The use of antidepressant medication in the general population has increased considerably in past decades, in particular the use of selective serotonin reuptake inhibitors (SSRIs). This increase in SSRI use may be explained by a broadened indication of SSRI, a different adverse effect profile, and a lower toxicity compared with classic tricyclic antidepressants. Yet, despite a more favorable ad...
متن کاملSerotonin reuptake inhibitor antidepressants (SSRIs) against atherosclerosis
Selective serotonin reuptake inhibitors (SSRIs) are a class of drug widely used for treatment of mood disorders, including depression and cardiovascular disease. A search for related articles in the PubMed database was attempted. It covered studies, reports, reviews and editorials of the last 5 years. Pro-inflammatory cytokines, such as TNF-α, IL-1 and IL-6, stimulate central serotonin (5-HT) n...
متن کاملInhibition of serotonin reuptake by antidepressants and upper gastrointestinal bleeding in elderly patients: retrospective cohort study.
OBJECTIVES To determine the association between inhibition of serotonin reuptake by antidepressants and upper gastrointestinal bleeding. DESIGN Retrospective cohort study from population based databases. SETTING Ontario, Canada. PARTICIPANTS 317 824 elderly people observed for more than 130 000 person years. The patients started taking an antidepressant between 1992 and 1998 and were grou...
متن کاملInhibition of serotonin reuptake by antidepressants and cerebral microbleeds in the general population.
BACKGROUND AND PURPOSE Serotonin reuptake inhibiting antidepressants decrease platelet aggregation. This may cause an increased risk of intracerebral hemorrhage. However, the risk of subclinical microbleeds, which are highly prevalent in middle-aged and elderly people, is unknown. We studied whether serotonin reuptake inhibiting antidepressants increase the frequency of cerebral microbleeds and...
متن کاملExposure to tricyclic and selective serotonin reuptake inhibitor antidepressants and the risk of hip fracture.
The use of tricyclic antidepressants is associated with an increased risk of hip fracture. Despite a better side effect profile, this adverse effect has also been reported for selective serotonin reuptake inhibitors. To determine whether these findings result from bias arising from the case-control method, the authors have performed a case-control analysis and a self-controlled case-series anal...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Neurology
سال: 2019
ISSN: 0028-3878,1526-632X
DOI: 10.1212/wnl.0000000000008060